All-en Hepatitis-en

Can adults with certain indications or medical
conditions receive the Hepatitis B vaccine?

By: Peduli Hati Bangsa Team
Date: September 7, 2023

Hepatitis B is a virus that can be prevented with a vaccine. Hepatitis B vaccine is currently not only recommended for children, but also for adults who have not been infected with Hepatitis B and want to get protection against Hepatitis B.

In 2021, the Indonesian Association of Internal Medicine Specialists (PAPDI) recommends that Hepatitis B vaccination be given to all adults without exception but it is best to have the HBsAg test prior to vaccination to ensure that the person has not been infected with Hepatitis B.

This recommendation applies without exception to certain conditions, including:

  1. Pregnancy
  2. Immunocompromised condition or immunodeficiency is a condition where the immune
    system is weakened (other than HIV)
  3. HIV infection (regardless of CD4 count)
  4. Men who have sex with men
  5. Heart disease, chronic lung disease, chronic alcoholism
  6. Asplenia (including elective splenectomy and persistent complement component deficiency)
  7. Chronic liver disease
  8. Kidney failure, end-stage kidney disease, hemodialysis patients
  9. Diabetes
  10. Health workers

Hepatitis B vaccination schedule for adults

  • The Hepatitis B vaccination schedule for adults is 0, 1, and 6 months.
  • Specifically for immunocompromised individuals or hemodialysis patients, PAPDI recommended a double dose vaccine (2 x 20 g/ml) for each injection at 0, 1, 2 and 6 months.

Additional notes:

  • In immunocompetent individuals, administration of booster doses is unnecessary.
  • In immunocompromised individuals, post-vaccination anti-Hbs antibody titers are tested periodically (a booster is given if the titer is < 10 mIU/mL)
  • In immunocompetent individuals, post-vaccination anti-Hbs antibody titers should be tested
  • 1 – 3 months after the last vaccination (protective if titer ≥ 10 mIU/mL).

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